Christmas Day, The first weekday after Christmas Day, New Year’s Day - Holiday Announcement 


Thank you for your support for the service in HKLAB.

The cut off time of sample collection will not be later than 13:00 on the Christmas Day (Dec 25th), The first weekday after Christmas Day (Dec 26th), New Year’s Day (Jan 1st, 2020) 

Further, the issue of Manlix Test reports may be postponed due to the holiday reason.

Please do not hesitate to contact us if you have queries.

Hong Kong Laboratory Co., Ltd
5 December 2019

 

HKLAB-Services
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  Accurate  
    To provide accurate laboratory test results by using the most effective and cutting edge technologies. The overall accuracy of the test ranges is approximately 99.4% or above.  
Services
Y-chromosome maternal serum test
Introduction Y-chromosome maternal serum test is annon-invasive prenatal DNA test (compared with the traditional invasive technology of amniocentesis) which is used to assess the risk for sex linked disease in fetus and to determine the possibility of paternity or non-paternity with the alleged father.
During pregnancy, a small amount of fetal DNA can get into the maternal blood stream through the placenta. Therefore, traces of fetal DNA can be detected and isolated, to reveal the conditions of fetal sex chromosome.
Specimen 6 ml EDTA blood X 2
Container K3EDTA tube / Cell-Free DNA BCT®
Cause for rejection Quantity not sufficient for analysis; Non-vacuumtube; Frozen specimen; Clotted specimen; Use of improper anticoagulant; Hemolysis
Storage instruction Specimen should be kept at 4°C (Cell-Free DNA BCT® specimen should be kept at room temperature)
Turn around time 1 working day*
*Urgent sample's turn around time is 6 hours
 
Y-chromosome maternal serum test (6 weeks) *
Introduction During pregnancy, a small amount of fetal DNA gets into the maternal blood through the placenta. This so called cell free fetal DNA (cffDNA) can first be observed as early as 6 weeks gestation, and the amount of cffDNA increases as the pregnancy progresses.
Compared with the general Y-chromosome maternal serum test, we also provide this kind of cutting-edge test for the women who have been pregnant for just 6 weeks to assess the risk of sex linked disease in fetus and to determine the possibility of paternity or non-paternity with the alleged father.
Specimen 6 ml EDTA blood X 2
Container K3EDTA tube / Cell-Free DNA BCT®
Cause for rejection Quantity not sufficient for analysis; Non-vacuumtube; Frozen specimen; Clotted specimen; Use of improper anticoagulant; Hemolysis
Storage instruction Specimen should be kept at 4°C (Cell-Free DNA BCT® specimen should be kept at room temperature)
Turn around time

1 working day *
*Urgent sample's turn around time is 6 hours

 
Y-chromosome maternal serum paternity test (Maternal blood + 1 alleged father)
Introduction Determine the chance of paternity or non-paternity in cases of disputed paternity; Prenatal parentage testing is a different type of parentage testing in which the father-child relationship can be identify before the child is born.
Specimen Mother:  6 ml EDTA blood X 3; 
Alleged father:  buccal swab X 2 or 6 ml EDTA blood X 1
Container K3EDTA tube / Cell-Free DNA BCT® / Sterile container
Cause for rejection Quantity not sufficient for analysis; Wet buccal swab; Non vacuumtube; Non-sterile container; Frozen specimen; Clotted specimen; Use of improper anticoagulant; Hemolysis
Storage instruction Buccal swabs can be kept at room temperature; Blood specimen should be kept at 4°C (Cell-Free DNA BCT® specimen should be kept at room temperature)
Turn around time 7 working day*
 
 
Paternity test of two samples (non-legal use)
Introduction Determine the chance of paternity or non-paternity in cases of disputed paternity.
Specimen 6mL EDTA blood X 1 or buccal swab X 2 (Per person)
Container K3EDTA tube / Cell-Free DNA BCT® / Sterile container
Cause for rejection Quantity not sufficient for analysis; Wet buccal swab; Non vacuum tube; Non-sterile container
Storage instruction Buccal swabs can be kept at room temperature; Blood specimen should be kept at 4°C (Cell-Free DNA BCT® specimen should be kept at room temperature)
Turn around time 5 working day*
Non-invasive fetal trisomY test--the NIFTY test
Introduction Using the latest next generation sequencing technology, NIFTY screens for the three most common trisomy conditions present at birth which are Down Syndrome, Edwards Syndrome and Patau Syndrome by analyzing the cell free fetal DNA circulating in maternal blood, compare with the invasive procedures such as amniocentesis, NIFTY not only poses no miscarriage risk to the mother or baby but also offers higher rates of accuracy. In addition, during the procedures of NIFTY test, we could also provide the sequence of fetal sex chromosome and then report its finial condition.
Specimen 10mL EDTA blood X 1
Container Cell-Free DNA BCT®
Cause for rejection Quantity not sufficient for analysis; Non vacuum tube
Storage instruction Cell-Free DNA BCT® specimen should be kept at room temperature
Turn around time 10 working day*
Breast cancer, ovarian cancer and genetic testing (NGS/Gene chip+NGS)
Introduction BRCA1 and BRCA2 (BRCA1/2) are genes that normally protect people from getting certain cancers. Women who inherit a mutation (mistake) in the BRCA1 or BRCA2 gene may increase greatly the risk of developing breast / ovarian cancers.  Currently our lab provides two more testings, firstly the NGS method (Next-Generation Sequencing) is available to detect the sequencing of 10 tumors which the susceptible genes are related to breast and ovarian cancers. Secondly, due to the gene chip could capture the whole exon of BRCA1 and BRCA2 genes, so a more comprehensive sequencing technique has been developed with NGS. Base on these two advanced technologies, the risks of developing cancers can be accurately detected and calculated, in addition, with the help of doctors you therefore can make earlier decision for cancer prevention and treatment.
Specimen 6mL EDTA blood X 1 or buccal swab X 1
Container K3EDTA tube / Cell-Free DNA BCT® / Sterile container
Cause for rejection Quantity not sufficient for analysis; Wet buccal swab; Non vacuum tube; Non-sterile container
Storage instruction Buccal swabscan be kept at room temperature, blood specimen should be kept at 4°C (Cell-Free DNA BCT® specimen should be kept at room temperature)
Turn around time 7~10 working days
Human papillomavirus (HPV)
Introduction Human papillomavirus (HPV) is a DNA virus which over 170 types have been identified, of which the high-risk HPV types, the 16 and 18 are known to cause around 70% of cervical cancer and the low-risk HPV types, the 6 and 11 are the etiological cause of genital warts. Genotype screening for this virus in the appropriate patients can prevent the progression of HPV-associated diseases. Our lab provides three kinds of genotyping for various HPV types, including HPV, Genotyping for 16, 18, HPV, Genotyping for 6, 11, 16, 18 and HPV, All-Genotypes (sequencing), of which the HPV All-Genotyping utilizing the cutting-edge sequence technology can discover more types of HPV that may be missing from from PCR test alone.
Specimen Vaginal swabs / Endocervical swab
Container 3 mL of solution in ThinPrep / PreservCyt vial
Cause for rejection Quantity not sufficient for analysis; Wet buccal swab; Non-sterile container
Storage instruction Swabs should be kept on 4 freezer. Bag specimens with tendency to leak during transport.
Turn around time 1~3 working days
Sexual Transmitted Diseases (STD)
Type 1. Chlamydia trachomatis
2. Neisseria gonorrhoeae
3. Mycoplasma genitalium
4. Ureaplasmaurealyticum
5. Trichomonas vaginalis
6. Candida albicans
7. Gardnerella vaginalis
8. Streptococcus A/B
Introduction Sexually transmitted diseases (STDs) are typically caused by bacteria, parasites and viruses and passed during sexual contact. Sometimes these infections can be transmitted non-sexually, such as from mother to infant during pregnancy or child birth, or through blood transfusions or shared needles. Most STDs affect both men and women, but in many cases the health problems they cause can be more severe for women. STDs often have no signs or symptoms, so it is important to do regular STDs screening, from which you can treat them before you can pass it on. This project contains 8 different types of venereal pathogenic agents screening which are relatively common. (Chlamydia trachomatis, Neisseria gonorrhoeae, Mycoplasma genitalium, Ureaplasmaurealyticum, Trichomonas vaginalis, Candida albicans, Gardnerella vaginalis, Streptococcus A/B)
Specimen Vaginal swabs / Endocervical swab/ Urethral swab / First catch urine-specific from men
Container Sterile and leak-proof container without preservatives
Cause for rejection Quantity not sufficient for analysis; Wet buccal swab; Non-sterile container;
Storage instruction Buccal swabs should be kept on 4 freezer
Turn around time 1 working days
HBV DNA quantitative viral load
Introduction Hepatitis B is a viral infection that attacks the liver and can cause both acute and chronic disease. The virus is transmitted through contact with the blood or other body fluids of an infected person. Once an estimation showed that 240 million people had been infected by chronical hepatitis B, therefore to perform the HBV DNA quantitative viral load test by mean of utilizing sensitive real time PCR is important, this can measure and quantify the HBV DNA, the level of baseline, help to assess the response in treatment, and as aid in managing the patients with chronic HBV disease undergoing antiviral therapy.
Specimen 6 mL EDTA blood X 1 or 2ml EDTA plasma X 1
Container K3EDTA tube
Cause for rejection Quantity not sufficient for analysis; Non vacuum tube; Clotted specimen; Use of improper anticoagulant; Hemolysis
Storage instruction EDTA blood should be kept at 4°C. EDTA plasma should be kept frozen.
Turn around time 2~3 working days
HBV multi-drugs resistance genotype
Introduction Antiviral drug resistance is the major cause of HBV reinfection after liver transplantation. The early diagnosis of antiviraldrug resistance and prompt intervention are critical. The best approach is to treat the patients with multidrug resistance although its unclear. Careful characterization of patient's mutations is therefore needed, as guide to make the choices of therapy to rescue the patient. 
Specimen 6 mL EDTA blood X 1 or 2ml EDTA plasma X 1
Container K3EDTA tube
Cause for rejection Quantity not sufficient for analysis; Non vacuumtube; Clotted specimen; Use of improper anticoagulant; Hemolysis
Storage instruction EDTA blood should be kept at 4°C. EDTA plasma should be kept frozen
Turn around time 3~4 working days
HCV RNA quantitative viral load
Introduction Hepatitis C is a liver disease caused by the HCV which mainly transmitted through contaminated blood. 80% of HCV-infected people show no signs of symptoms and 20% of chronic HCV-infected people will develop cirrhosis. Therefore, it is important to detect and quantify Hepatitis C Virus (HCV) RNA in early stage to prevent the progression of HCV infection. HCV RNA quantitative viral load test is a reliable and sensitive technology, whose result can be used as an important index for monitoring the drug efficacy of viral hepatitis treatment.
Specimen 2ml EDTA plasma X 1
Container K3EDTA tube
Cause for rejection Quantity not sufficient for analysis; Non vacuum tube; Clotted specimen; Use of improper anticoagulant
Storage instruction EDTA plasma should be kept frozen
Turn around time 2~3 working days
HCV genotype (CE-IVD)
Introduction As there are different HCV subtypes of (HCV) RNA and each subtype has response to drug treatment, thus HCV genotyping is necessary to provide doctors with clear HCV subtype information for adopting the most appropriate drug treatment for HCV patients.
Specimen 2ml EDTA plasma X 1
Container K3EDTA tube
Cause for rejection Quantity not sufficient for analysis; Non vacuum tube; Clotted specimen; Use of improper anticoagulant; hemolysis
Storage instruction EDTA plasma should be kept frozen.
Turn around time 3~4 working days
EBV, Qualitative
Introduction The EBV (Epstein Barr) PCR Qualitative test is used for screening Epstein-Barr Virus. PCR testing can be more sensitive than standard antibody testing for EBV. In cases when antibody tests for EBV fail to produce definitive results, a PCR test may be more useful. Results for this test are qualitative, meaning they provide a positive or negative response.
Specimen Nasopharyngeal Swab X 1 or 3 ml EDTA Blood X 1
Container Sterile container / EDTA tube
Cause for rejection Quantity not sufficient for analysis; Wet buccal swab; Non-sterile container
Storage instruction Swabs can be kept at room temperature. blood specimen should be kept at 4°C
Turn around time 2 working days
EBV, Viral Load, Quantitative
Introduction The target cell for EBV infection is the B lymphocyte. Immunocompromised patients, lacking antibody to EBV, are at risk of acute EBV infection that may cause lymphoproliferative disorders in organ transplant recipients. Therefore, serial determination of blood specimens from patients may be necessary to monitor the risk of development of post-transplant lymphoproliferative disorders.
Specimen 6 ml EDTA Blood X 1
Container EDTA tube
Cause for rejection Quantity not sufficient for analysis; Non vacuum tube; Clotted specimen; Use of improper anticoagulant; Hemolysis
Storage Iinstruction EDTA blood specimen should be kept at 4°C
Turn around time 2 working days

 

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Address Unit F,8/F,Valiant Industrial Centre,2-12 Au Pui Wan Street,Fo Tan,N.T.,Hong Kong
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